James                          Lloyd-Smith

James Lloyd-Smith

Professor

email:   jlloydsmith@ucla.edu
phone:  310-206-8207
office:  Terasaki Life Sciences Building 4135
lab:  Terasaki Life Sciences Building 4000
[website]



Recent Courses

BIOMATH 596 - Directed Individual Study or Research in Biomathematics
EE BIOL 201 - Introduction to R for Ecology and Evolutionary Biology
EE BIOL 596 - Directed Individual (or Tutorial) Studies


Education

B.Sc.(Hon), Physics And Chemistry, Queen's University 1996
M.Sc., Physics, University of British Columbia 1999
PhD, Biophysics, University of California, Berkeley 2005



Research Interests

I study the ecological and evolutionary dynamics of infectious disease in animal and human populations, and at the animal-human interface where novel human pathogens such as SARS or pandemic influenza can emerge. By combining theoretical models with data, I aim to deepen our understanding of fundamental principles of disease transmission and adaptation, and apply those principles to interpret observed patterns, uncover driving mechanisms, and design effective control policies. I work on a diverse range of disease-host systems, including leptospirosis in California sea lions, monkeypox in humans and wildlife in central Africa, and SARS and other emerging diseases in human populations.


Selected Publications

, "Challenges in modelling infectious disease dynamics", Epidemics, Lloyd-Smith, J.O., Mollison, D., Metcalf, C.J.E., Klepac, P., Heesterbeek, J.A.P.(Eds.), 10 : - (2015) .

Buhnerkempe, M.G., Gostic, K.M., Park, M., Ahsan, P., Belser, J.A., Lloyd-Smith, J.O., "Mapping influenza transmission in the ferret model to transmission in humans", eLife, Lloyd-Smith, J.O., Mollison, D., Metcalf, C.J.E., Klepac, P., Heesterbeek, J.A.P.(Eds.), 4 : e07969- (2015) .

Biek, R., Pybus, O.G., Lloyd-Smith, J.O., Didelot, X., "Measurably evolving pathogens in the genomic era", Trends in Ecology and Evolution, Lloyd-Smith, J.O., Mollison, D., Metcalf, C.J.E., Klepac, P., Heesterbeek, J.A.P.(Eds.), 30 : 306-313 (2015) .

Gostic, K.M., Kucharski, A.J., Lloyd-Smith, J.O., "Effectiveness of traveller screening for emerging pathogens is shaped by epidemiology and natural history of infection", eLife, Lloyd-Smith, J.O., Mollison, D., Metcalf, C.J.E., Klepac, P., Heesterbeek, J.A.P.(Eds.), 4 : e05564- (2015) .

Heesterbeek, H., Anderson, R., Andreasen, V., Bansal, S., De Angelis, D., Dye, C., Eames, K., Edmunds, J., Frost, S, Funk, S., Hollingsworth, D., House, T., Isham, V., Klepac, P., Lessler, J., Lloyd-Smith, J., Metcalf, J., Mollison, D., Pellis, L., Pulliam, J., Roberts, M., Viboud, C., Isaac Newton Institute IDD Collaboration, "Modeling infectious disease dynamics in the complex landscape of global health", Science, Lloyd-Smith, J.O., Mollison, D., Metcalf, C.J.E., Klepac, P., Heesterbeek, J.A.P.(Eds.), 347 : aaa4339-1-aaa4339-10 (2015) .

Ke, R., Loverdo, C., Qi, H., Sun, R., Lloyd-Smith, J.O., "Rational design and adaptive management of combination therapies for Hepatitis C virus infection", PLOS Computational Biology, Lloyd-Smith, J.O., Mollison, D., Metcalf, C.J.E., Klepac, P., Heesterbeek, J.A.P.(Eds.), 11 : e1004040- (2015) .

Gog, J.R., Pellis, L., Wood, J.L.N., McLean, A.R., Arinaminpathy, N., Lloyd-Smith, J.O., "Seven challenges in modelling pathogen dynamics within-host and across scales", Epidemics, Lloyd-Smith, J.O., Mollison, D., Metcalf, C.J.E., Klepac, P., Heesterbeek, J.A.P.(Eds.), 10 : 45-48 (2015) .

Lloyd-Smith, J.O., Funk, S., McLean, A.R., Riley, S., Wood, J.L.N., "Nine challenges in modelling the emergence of novel pathogens", Epidemics, Lloyd-Smith, J.O., Mollison, D., Metcalf, C.J.E., Klepac, P., Heesterbeek, J.A.P.(Eds.), 10 : 35-39 (2015) .

Buhnerkempe, M.G., Roberts, M.G., Dobson, A.P., Heesterbeek, H., Hudson, P.J., Lloyd-Smith, J.O., "Eight challenges in modelling disease ecology in multi-host, multi-agent systems", Epidemics, Lloyd-Smith, J.O., Mollison, D., Metcalf, C.J.E., Klepac, P., Heesterbeek, J.A.P.(Eds.), 10 : 26-30 (2015) .

Lloyd-Smith, J.O., Mollison, D., Metcalf, C.J.E., Klepac, P., Heesterbeek, J.A.P., "Challenges in modelling infectious disease dynamics: preface", Epidemics, Lloyd-Smith, J.O., Mollison, D., Metcalf, C.J.E., Klepac, P., Heesterbeek, J.A.P.(Eds.), 10 : iii-iv (2015) .