I am interested in using whole genome and exome sequencing to explore the ways in which demographic history impacts the burden of deleterious variation in threatened species. I am particularly focused on the sea otter, using modern and ancient sea otter DNA to determine its history of population bottlenecks and levels of genomic diversity. I sequenced, assembled and annotated the sea otter genome de novo as part of this effort, and have explored comparative genomic questions for the sea otter and giant otter. I make extensive use of simulations in my research as a way to generate null hypotheses based on inferred demographic histories, and have explored the relative merits of different demographic inference methods.
Beichman, Huerta-Sanchez, Lohmueller (in press) Using Genomic Data to Infer Historic Population Dynamics of Nonmodel Organisms Annual Review of Ecology, Evolution, and Systematics
Beichman, Phung, Lohmueller (2017) Comparison of Single Genome and Allele Frequency Data Reveals Discordant Demographic Histories G3: Genes, Genomes, Genetics
Sanders, Beichman, Roman, Scott, Emerson, McCarthy, Girguis (2015) Baleen whales host a unique gut microbiome with similarities to both carnivores and herbivores Nature Communications
2012 Harvard University A.B. summa cum laude Organismic & Evolutionary Biology