May 12 2014

4:00 pm LSB 2320

Andrew Read
Director, Center for Infectious Disease Dynamics, Alumni Professor, Department of Biological Sciences and Professor of Entomology, Pennsylvania State University

Pathogen Evolution in a Vaccinated World


Drug resistant pathogens are common, but vaccine resistant pathogens are not. I will nonetheless argue that not all vaccines will be evolution-proof. In theory and in practice, immunization can drive the evolution of a variety of pathogen phenotypes, many of which can erode vaccine efficacy. I will discuss our experimental work which shows that some vaccines can cause the evolution of pathogens which induce more severe disease in the unvaccinated.















































































































































































































































































































































































































































































































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