November 17 2010

12:00 LSB 2320

Nicholas Holland
Scripps Institution of Oceanography, UC San Diego

Homology in the age of devo-evo


Comparative biology is grounded on homology, which is a much messier subject than Wikipedia would lead one to believe. During the last 200 years, concepts of homology have changed, whereas the criteria for recognizing homologies have been relatively stabile. The history of the subject will be traced starting with Belon (1555), through days of pure anatomy, through the addition of molecular sequence data in the 1960s, and through the discovery of conserved developmental genes in the 1980s that gave rise to the birth of devo-evo. The enduring relevance of concepts and criteria of homology for the practice of devo-evo is examined with special attention to mapping the central nervous system of the basal chordate, amphioxus.















































































































































































































































































































































































































































































































this is idtest: