May 30 2019

5:00 pm 1100 TLSB

EcoEvoPub Series

Graduate Student Presentations


Department of Ecology and Evolutionary Biology
Jacobs Lab

“CpG Content as a Proxy for Historical DNA Methylation”

The relative CpG (cytosine-phospho-guanine) content can be considered as the ‘footprint’ of DNA methylation. Interestingly, DNA methylation has left very different footprints in different animal taxa, suggesting they have undergone different histories of DNA methylation on an evolutionary scale. In Cnidaria, parasitic species in particular seem to be more likely to have lost DNA methylation. Some other species also show interesting CpG distribution patterns, especially when combined with analyses of methylation-related genes. Overall, CpG content can be a good first look at DNA methylation of a species of interest, without having to perform methylation sequencing.

Thursday, May 30th, 2019 @ 5 PM
1100 Terasaki Life Sciences Building [TLSB]











































































































































































































































































































































































































































































































































































































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