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Selected Publications

  • Yang WY, Novembre J, Eskin E, Halperin E. (2012). A model-based approach for analysis of spatial structure in genetic data. Nature Genetics. [pdf][supp info]

  • Nelson MR*, Wegmann D*, Ehm MG, Kessner D, Jean PS, Verzilli C, Shen J, Tang Z, Bacanu SA, Fraser D, Warren L, Aponte J, Zawistowski M, Liu X, Zhang H, Zhang Y, Li J, Li Y, Li L, Woollard P, Topp S, Hall MD, Nangle K, Wang J, Abecasis G, Cardon LR, Zöllner S, Whittaker JC, Chissoe SL, Novembre J*, Mooser V*. (2012). An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People. Science. [abstract][pdf]

  • Novembre J, Ramachandran S. (2011). Perspectives on human population structure at the cusp of the sequencing era. Annual Review of Genomics and Human Genetics. [pdf].

  • Wegmann D, Kessner D, Veeramah KR, Mathias RA, Nicolae DL, Yanek LR, Sun YV, Torgerson DG, Rafaels N, Mosely T, Becker LC, Ruczinski I, Beaty TH, Kardia SLR, Meyers D, Barnes KC, Becker DM, Freimer N, Novembre J. (2011). Recombination rates in admixed individuals revealed by ancestry–based inference. Nature Genetics (online ahead of print) [pdf][supp info pdf].

  • Von Holdt BM, Pollinger JP, Earl DA, Knowles JC, Boyko AR, Parker H, Geffen E, Pilot M, Jedrzejewski W, Jedrzejewska B, Sidorovich V, Greco C, Randi E, Musiani M, Kays R, Bustamante CD, Ostrander EA, Novembre J, Wayne RK. (2011) Genome-wide perspective on the evolutionary history of enigmatic wolf-like canids. Genome Research (online ahead of print) [pdf].

  • Veeramah KR*, Tönjes A*, Kovacs P, Gross A, Wegmann D, Geary P, Gasperikova D, Klimes I, Scholz M, Novembre J, Stumvoll M. (2011) Genetic variation in the Sorbs of eastern Germany in the context of broader European genetic diversity. European Journal of Human Genetics (online ahead of print)[pdf].

  • Vonholdt BM, Pollinger JP, Lohmueller KE, Han E, Parker HG, Quignon P, Degenhardt JD, Boyko AR, Earl DA, Auton A, Reynolds A, Bryc K, Brisbin A, Knowles JC, Mosher DS, Spady TC, Elkahloun A, Geffen E, Pilot M, Jedrzejewski W, Greco C, Randi E, Bannasch D, Wilton A, Shearman J, Musiani M, Cargill M, Jones PG, Qian Z, Huang W, Ding ZL, Zhang YP, Bustamante CD, Ostrander EA, Novembre J, Wayne RK. (2010) Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication. Nature 464:898-902. [pdf][supp info pdf]

  • François O, Currat M, Ray N, Han E, Excoffier L, Novembre J. (2010) Principal component analysis under population genetic models of range expansions and admixture. Molecular Biology and Evolution. [pdf]

  • Novembre J, Di Rienzo A. (2009) Spatial patterns of variation due to natural selection in humans. Nat Rev Genetics 10:745-755. [pdf]

  • Alexander DH, Novembre J, Lange K. (2009) Fast model-based estimation of ancestry in unrelated individuals. Genome Research 19:1655-1664. [pdf][supp info pdf]

  • Novembre J, Slatkin M. (2009) Likelihood-based inference in isolation-by-distance models using the spatial distribution of low-frequency alleles. Evolution 63:2914-2925. [pdf][supp info pdf].

  • Coop G, Pickrell JK, Novembre J, Kudaravalli S, Li J, Absher D, Myers RM, Cavalli-Sforza LL, Feldman MW, Pritchard JK. (2009) The role of geography in human adaptation. PloS Genetics 5:e1000500. [pdf]

  • Pickrell JK, Coop G, Novembre J, Kudaravalli S, Li J, Absher D, Srinivasan B, Barsh GS, Myers RM, Feldman MW, Prichard JK. (2009) Signals of recent positive selection in a worldwide sample of human populations. Genome Research 19:826-837. [pdf][supp info]

  • Auton A, Byrc K, Boyko AR, Lohmueller KE, Novembre J, Reynolds A, Indap A, Wright MH, Degenhardt J, Gutenkunst RN, King KS, Nelson MR, Bustamante, CD. (2009) Global distribution of genomic diversity underscores rich complex history of continental human populations. Genome Research 19:795-803[pdf][supp info][supp Excel table]

  • Novembre J, Johnson T, Bryc K, Kutalik Z, Boyko AR, Auton A, Indap A, King KS, Bergman S, Nelson MR, Stephens M, Bustamante CD. (2008) Genes mirror geography within Europe. Nature 456:98-101. [pdf][supp info pdf]

  • Nelson MR, Bryc K, King KS, Indap A, Boyko AR, Novembre J, Maruyama Y, Waterworth DM, Waeber G, Vollenweider P, Oskenberg JR, Hauser SL, Stirnadel H, Kooner JS, Chambers JC, Jones B, Mooser V, Bustamante CD, Rosed AD, Burns DK, Ehm MG, Lai EH. (2008) The Population Reference Sample (POPRES): a resource for population, disease, and pharmacological genetics research. American Journal of Human Genetics 83:347-358. [pdf]

  • Reiner AP, Barber MJ, Guan Y, Ridker PM, Lange LA, Chasman DI, Walston JD, Cooper GM, Jenny NS, Rieder MJ, Durda JP, Smith JD, Novembre J, Tracy RP, Rotter JI, Stephens M, Nickerson DA, Krauss RM. (2008) Polymorphisms of the HNF1A Gene Encoding Hepatocyte Nuclear Factor-1alpha are Associated with C-Reactive Protein. American Journal of Human Genetics 82:1193-1201. [pdf]

  • Novembre, J, Stephens, M. (2008) Interpreting principal components analyses of spatial population genetic variation. Nature Genetics 40:646-649[pdf] [supp info pdf]

  • Novembre, J*, Pritchard, JK, Coop, G.* (2007) Adaptive drool in the gene pool. Nature Genetics 39:1188-1190. [pdf]

  • Rosenblum, EB*, Novembre, J.* (2007) Ascertainment bias in spatially structured populations: A case study in the Eastern Fence Lizard. Journal of Heredity 98(4):331-336. [pdf]

  • Novembre, J, Galvani, AP, Slatkin, M. (2005) The geographic spread of the CCR5-Delta32 HIV-resistance mutation. PLOS Biology 3(11):e397. [pdf] [synopsis pdf]

  • Galvani, AP, Novembre, J. (2005) The evolutionary history of the CCR5-Delta32 HIV-resistance mutation. Microbes and Infection 7:302-309. [pdf]

  • Anderson, EC, Novembre, J. (2003) Finding haplotype block boundaries using the minimum description length principle. American Journal of Human Genetics 73(2):336-354.[pdf]

  • Herbeck, J, Novembre, J. (2003) Codon usage patterns in cytochrome oxidase I across multiple insect orders. Journal of Molecular Evolution 56(6):691-701. [pdf]

  • Slatkin, M., Novembre, J. (2003) Appendix to paper by Wall and Herbeck. Journal of Molecular Evolution 56(6):689-690.[pdf]

  • Novembre, J. (2002) Accounting for background nucleotide composition when measuring codon usage bias. Molecular Biology and Evolution 19(8):1390-1394. [pdf]

  • Excoffier, L, Novembre, J, Schneider, S. (2000) SIMCOAL: a general coalescent program for simulation of molecular data in interconnected populations with arbitrary demography. Journal of Heredity 91:506-509. [pdf]

  • * authors contributed equally