People

Principal Investigator:

 

Kirk Lohmueller

Kirk is an Assistant Professor in the Department of Ecology and Evolutionary Biology at UCLA. He is broadly interested in evolutionary and population genetics and genomics. Previously, he was a Miller Fellow at UC Berkeley where he worked with Rasmus Nielsen. Kirk received his PhD from Cornell University where he worked with Andy Clark and Carlos Bustamante.

Graduate Students:

Annabel Beichman 

Annabel is a Ph.D. student in EEB, co-advised by Kirk Lohmueller and Robert Wayne. She is interested in using population genetics to investigate the effects of severe population bottlenecks on the sea otter genome, including changes in genome-wide diversity and the accumulation of harmful mutations. She is also working to estimate the demographic history of human populations using a coalescent approach and is investigating the effects of environmental pollutants on the gene expression of long-beaked common dolphins. Her past research includes using next-generation sequencing to investigate the baleen whale gut microbiome and surveying adaptive variation in purple sea urchins across the California coast.

Jazlyn Mooney 

Jazlyn is a PhD student in the Genetics and Genomics program. She is interested in implementing techniques from evolutionary anthropology, population genetics, and bioinformatics to examine patterns of human genetic variation. She is currently investigating the relationship between runs of homozygosity in the human genome and the distribution of deleterious variants.

Bernard Kim

Bernard is a PhD student in the EEB program and is jointly advised by Kirk Lohmueller and Pam Yeh. He is particularly interested in the distribution of fitness effects (DFE) of new mutations. He is developing to computational methods to infer the DFE in humans and other lineages.

Tanya Phung

Tanya is a PhD student in the Bioinformatics program. She is currently working on understanding why genetic variation is reduced at linked neutral sites. She is also developing methods to disentangle which evolutionary forces drive the pattern of genetic variation across the genome. Tanya previously was an undergraduate researcher in the Laub lab at MIT where she investigated the specificity of toxin-antitoxin systems in bacteria.

Postdoctoral Researchers:

Christian Huber 

Christian is tackling a number of important projects in the Lohmueller lab. Much of his current research focuses on using whole-genome population sequencing data to infer the distribution of fitness effects (DFE) of new mutations in different species.

Christian did his master studies in physical anthropology and geometric morphometrics. He then switched to population genetics for his PhD at the Vienna Graduate School of Population Genetics, supervised by Ines Hellmann, Magnus Nordborg and Joachim Hermission. The topic of his thesis was the detection of selective sweeps on top of population structure and background selection, analyzing data from Arabidopsis thaliana and humans.

 

Clare Marsden

Clare joined the Lohmueller lab in September 2013 on a Computational Biosciences Institute Postdoctoral Fellowship in Bioinformatics. She is currently involved in two research projects. The first, which is being conducted in collaboration with Robert Wayne, is investigating signatures of demography and selection in the genomes of the domestic dog and their wild progenitor, the grey wolf. The second is a forensic genetics project focused on the development of new analytical approaches for low template and mixed DNA samples. She also conducts bioinformatics training workshops to UCLA graduate students, post docs and staff as part of the UCLA computational sciences initiative collaboratory. 

Clare previously was a postdoc at the University of California Davis conducting research into the population genetics and genomics of two African mosquito malaria vectors; Anopheles gambiae s.s. and Anopheles arabiensis.  She completed her PhD on the evolutionary and ecological genetics of the endangered African wild dog (Lycaon pictus) at the University of Glasgow.

 

Ying Zhen 

Ying is a postdoc working jointly with Kirk Lohmueller and Tom Smith. Her current research focuses on using large scale population genetic data to learn about the demographic history and natural selection across a diverse array of non-model taxa from Central Africa.
Ying previously was a postdoc with Peter Andolfatto at Princeton University, working on convergent evolution in an herbivore community and evolution of gene expression in Drosophila species. She received her Ph.D. from Kansas State University where she worked with Mark Ungerer on natural variation of freezing tolerance in Arabidopsis.

Undergraduates:

Jesse Garcia

Jesse is an EEB major at UCLA who is interested in population genetics and conservation biology. Jesse is currently working on using simulations to examine the effects of inbreeding on deleterious variants.

Lab Alumni:

Diego Ortega Del Vecchyo Diego was a PhD student in the Bioinformatics program jointly advised by Kirk and John Novembre. His research focused on exploring how haplotypic linkage disequilibrium patterns are affected by purifying selection. He used the information contained in those patterns to infer the distribution of the strength of negative selection across the human genome. He is currently a postdoc with Monty Slatkin at UC Berkeley.

Charleston Chiang Charleston was a postodctoral fellow with Kirk and John Novembre at University of Chicago. His research focused on using large scale population genotyping and sequencing data to learn about past population history, detect signals of polygenic selection, and infer mutation rates. He is currently a postdoctoral fellow with Nelson Freimer at UCLA.

Megan Roytman Megan was a Bioinformatics rotation student in the Lohmueller lab in spring 2014. She joined the Pasaniuc lab.

Amy Chow Amy was an undergaduate student in the Lohmueller lab. She is currently a MS graduate student in mechanical engineering at San Diego Sate.